Is CME open on Wednesday 5 December 2018?

No. CME is closed on Wednesday 5 December 2018 for Market holiday. It reopens on Thursday 6 December 2018.

Market holiday

Related markets on 5 Dec 2018

CME Equity	National Day of Mourning for former President George H. W. Bush
NYSE	National Day of Mourning for former President George H. W. Bush
Nasdaq	National Day of Mourning for former President George H. W. Bush
CFE	National Day of Mourning for former President George H. W. Bush
NYMEX Energy	17:00^{−1 previous day}–16:00
TSX	09:30–16:00
B3	10:00–17:00
COMEX	17:00^{−1 previous day}–16:00
CME FX	17:00^{−1 previous day}–16:00
CBOT Rates	National Day of Mourning for former President George H. W. Bush